Botox, developed by Allergan, is the most well-known wrinkle relaxer on the market and was the first botulinum toxin approved by the FDA in 2002. It’s designed with accessory proteins that help stabilize the formula, ensuring its efficacy and longevity. Ideal for those new to wrinkle treatments, Botox takes about two weeks to show full effects, which typically last up to three months. Its long-standing reputation and extensive track record make it a reliable choice for achieving smoother skin.